Symptomatic congenital CMV infection after recurrent maternal infection

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Review and meta-analysis of the epidemiology of congenital cytomegalovirus (CMV) infection.

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Cytomegalovirus (CMV) infection is the most common congenital infection with the incidence varying from 1% to 3%. At birth, approximately 10% of intrauterine infected infants demonstrate clinical symptoms and signs of infection which carries a risk of morbidity and mortality. Perinatal infection occurs in the contact of an infant with secretions and excretions of the mother with active CMV infe...

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It is generally accepted that the risk for fetal infection is greatest with maternal primary cytomegalovirus CMV infection and much less likely with recurrent infection. Here, we report a fatal case of congenital CMV infection following recurrent maternal infection after a 7-year interval. A 3-month-old female baby presented with fever, jaundice, vomiting and stopping breast-feeding. Physical e...

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Symptomatic congenital cytomegalovirus disease following non-primary maternal infection: a retrospective cohort study

BACKGROUND Scarce data exist about screening, diagnosis and prognosis of non-primary Cytomegalovirus (CMV) during pregnancy. We aimed to examine antenatal diagnosis of maternal non-primary CMV infection and to identify risk factors for congenial CMV disease. METHODS Retrospective cohort of 107 neonates with congenital symptomatic CMV infection, following either primary (n = 95) or non-primary...

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تاریخ انتشار 2017